Examine reveals ladies lead in covid antibody response

Analysis Scholar Kate Petersen

COVID-19 vaccines work extra successfully on ladies than males, a brand new Australian Catholic College (ACU) research has discovered.

Scholar researcher Kate Petersen, 22, from ACU’s College of Behavioural and Well being Sciences mentioned all of the research’s members produced an immune response to their COVID-19 vaccination, no matter whether or not a Pfizer, AstraZeneca, Moderna or Novavax dose has been administered.

“What was fascinating, nonetheless, was that we discovered that girls produced extra antibodies than males,” she mentioned.

“We wished to search out out if the vaccines labored so it was useful to study that everyone had a response.

“The distinction within the antibody responses between women and men raises the query of the potential want for a higher push for males to have boosters.”

The research analysed blood samples taken from 40 members older than 18 who had beforehand acquired a vaccine in opposition to COVID-19. It additionally examined related medical historical past (age, gender, well being standing and common drugs) more likely to impression the immune response following the vaccination.

The honours mission, Human Immunoglobulin G Antibody Responses to COVID-19 Vaccination, was among the many first to look at antibody responses because the scientific trials performed by every of the pharmaceutical corporations.

Researcher Dr Roger Lord.

Bachelor of Biomedical Science Honours pupil, Ms Petersen was a part of a crew that included supervisor Dr Roger Lord, a researcher with in depth immunology and vaccine improvement expertise, and senior lecturer Dr Francesca Fernandez.

The imply antibody stage was 320 items/mL for ladies and 255 items/mL for males. On common, ladies produced 65 items/mL extra antibodies than males.

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The research was Ms Petersen’s first alternative to contribute “arms on” to a analysis mission.

“I’d by no means thought of doing something like this till the chance got here up final 12 months,” she mentioned.

“I couldn’t think about sitting in a lab on my own so the possibility to mix the diagnostic expertise with human interplay is one thing I discover actually attention-grabbing and stimulating.”

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Ian Meikle, editor